Tuesday, December 26, 2017

#34. The Pilgrim and the Whale [evolutionary psychology]


Red, theory; black, fact




Just as the whale must hold its breath to obtain its food from the sea, so must a human restrain his or her anger to obtain a paycheck from society. 

The ecological niche occupied by the whale places two of its drives in contradiction: the drive to eat and the drive to breathe. In humans, the contradictory drives are eating and dispersal.

Dispersal is a biological process tending to expand the geographical range of a species. Left to itself, the range shrinks inexorably because of natural disasters such as fire, frost, famine, drought, and pestilence wiping out all members of a given species in a given habitat. When each habitat occupied by the species has had its disaster, the species will be extinct if it has not been dispersing all along. Dispersal re-populates the devastated habitats as they become able to support life again, thereby staving off extinction.

Unfortunately, human dispersal begins with fraught political contests. As soon as one side gets the upper hand, the other must flee. Result: mass migration, i.e., dispersal. Most human anger is really dispersal hunger. However, when people get mad, they break stuff. Stuff like buildings, airports, factories, railway lines, etc. This is the infrastructure on which we all depend for our survival. Because our ecological niche is in a fragile built environment, we are required to compromise between eating and dispersal. And there you have my analysis of the biological roots of our unhappiness.

This contradiction in drives is the ultimate reason why every able-bodied Muslim must make the pilgrimage to Mecca at least once in their lifetime: it mellows them out by giving something to the dispersal drive. The same effect would explain the fact that first-generation immigrants are generally more law-abiding than the natives.

Other institutions that may exist to relieve dispersal hunger are: tourism, the fitness movement, Seeing the World, conference-going, joining the Navy, going away to university, visiting faraway relatives for the holidays, companies moving their employees around a lot, and others I'll think of tomorrow morning.

Catholicism is also famous for its tradition of pilgrimage, to such places as Jerusalem, Rome, Lourdes, and Santiago de Compostela, the latter still popular today. Protestantism has no such tradition, however.

Judaism, Hinduism, and Buddhism all have strong traditions of pilgrimage, and the practice is so universal that it has been proposed as a Jungian archetype by Clift and Clift. I myself walk a lot, because I cannot afford a car or a downtown apartment close to all the amenities. But is that the ultimate reason? 

Happy trails.

Sunday, December 17, 2017

#33. Emotions [evolutionary psychology, genetics, neuroscience]

EP   NE   GE

Red, theory; black, fact



All sexually reproducing species may have a long-range guidance system that that could be called proxy natural selection, or preferably, post-zygotic gamete selection (PGS). This is basically a fast form of evolution in which individual cells, the gametes, are the units of selection, not individuals. Selection is conjectured to happen post-zygotically (i.e., sometime after the beginning of development, or even in adulthood) but is retroactive to the egg and sperm that came together to create the individual. Each gamete is potentially unique because of the crossing-over genetic rearrangements that happen during its maturation. This theory explains the biological purpose of this further layer of uniqueness beyond that due to the sexual mixing of chromosomes, which would otherwise appear to be redundant.

Our emotions are conjectured to be programmed by species-replacement group selection and to serve as proxies for increases and decreases in the fitness of our entire species.

A further correlate of an emotion beyond the cognitive and autonomic-nervous-system components would be the neurohumoral component, expressed as chemical releasing and inhibiting factors that enter the general circulation via the portal vessels of the hypothalamus, blood vessels which are conventionally described as affecting only the anterior pituitary gland. These factors may reach the stem-like cells that mature into egg and sperm, where they set reversible epigenetic controls on the level of crossing-over that will occur during differentiation. Large amounts of crossing-over are viewed as retroactively penalizing the gametes leading to the individual by obfuscating or overwriting with noise specifically the genetic uniqueness of said original gametes. In contrast, low levels of further crossing-over reward the original gametes with high penetrance into the next generation. Here we have all the essential ingredients of classical natural selection, and all the potential, in a process that solves problems on an historical timescale.

Crossing-over happens only between homologous chromosomes, which are the paternal and maternal copies of the same chromosome. Human cells have 46 chromosomes because they have 23 pairs of homologous chromosomes. The homologous-chromosome-specificity of crossing-over suggests that the grand optimization problem that is human evolution has been broken down into 23 smaller sub-problems for the needs of the PGS process, each of which can be solved independently, without interactions with any of the other 22, and which involves a 23-fold reduction in the number of variables that must be simultaneously optimized. In computing, this problem-fragmentation strategy greatly increases the speed of optimization. I conjecture that it is one of the features that makes PGS faster than classical natural selection.

However, we now need 23 independent neurohumoral factors descending in the bloodstream from brain to testis or (fetal) ovary, each capable of setting the crossing-over propensity of one specific pair of homologous chromosomes. Each one will require its own specific receptor on the surface of the target oogonia or spermatogonia. In the literature, I already find a strange diversity of cell-surface receptors on the spermatogonia. I predict that the number of such receptors known to science will increase to at least 23. None of this is Lamarkism, because nervous-system control would be over the standard deviation of behavioral traits, not their averages.

Naively, this theory also appears to require 23 second messengers to transfer the signals from cell surface to nucleus, which sounds excessive. Perhaps the second messengers form a combinatorial code, which would reduce the number required by humans to log2 (23) = 4.52, or 5 in round numbers. This is much better. Exactly five second-messenger systems are known, these being based on: cyclic AMP, inositol triphosphate, cyclic GMP, arachidonic acid, and small GTPases (e.g., ras). However, many mammalian species have many more than the 32 chromosome pairs needed to saturate a 5-bit address space. If we expand the above list of second messengers with the addition of the calcium/calmodulin complex, the address space expands to 64 pairs of homologous chromosomes, for a total ploidy of 128. This seems sufficient to accommodate all the mammals. Thus, a combinatorial second-messenger code representable as a five- or six-bit binary integer in most organisms would control the deposition of the epigenetic marks controlling crossing-over propensity.

If the above code works for transcription as well as epigenetic modification, then applying whatever stimuli it takes to produce a definite combinatorial second-messenger state inside the cell will activate one specific chromosome for transcription, so that the progeny of the affected cell will develop into whatever that chromosome specifies, be it an organ, a system, or something else. And there you may have the long-sought key to programming stem cells. You're welcome.

The requirement that the evolution of each chromosome contribute independently to the total increase in fitness suggests that a chromosome specifies a system, like the nervous system or the digestive system. We seem to have only 11 systems, not 23, but more may be defined in the future.

A related concept is that a chromosome specifies an ancestral, generic cell type, like glial cells (4 subtypes known) or muscle cells (3 subtypes known). The great diversity of the neurons suggest that they must be reclassified into multiple basic types, perhaps along the lines suggested by the functional classification of the cranial nerves: general somatic, general visceral, and special somatic (i.e., specific senses).

A third concept for function assignment to homologous pairs of chromosomes postulates a hypothetical maximally divided genome in which each cell type has its own chromosome pair, a state conjectured to seldom occur in nature. Co-evolution of clusters of cell types (e.g., neurons and glia; bone and cartilage) would create selection pressure for the underlying cell-type-specific chromosomes to become covalently linked into the larger chromosomes that we see in the actual karyotypes. Thus, each observed homologous pair would correspond to a few cell types that are currently co-evolving, which seems to return us to the system or organ concept. 

Wednesday, September 13, 2017

#32. Big-electron Theory [physics]


Red, theory; black, fact




Some of the paradoxes and weirdness of quantum mechanics can be dispelled if we assume that any particle that can be diffracted isn't really there: we are only looking at the center of spherical symmetry of a much larger, possibly cosmologically large, wave function. Furthermore, this center of symmetry is only an abstraction, like the north pole of the Earth. Like the fields that we impute to them, quantum particles would have a wave function amplitude that decreases asymptotically to zero with distance from the center, and thus would have no well defined outer boundary: particles or wave functions are "expansive."

Elementary particles seem submicroscopic in size because the wavelength of the corresponding wave functions is often submicroscopic, which imposes a requirement for the centers of symmetry of two such "particles" to coincide with very great precision before an interaction can be observed. This would be the case if the default interaction were characterized by destructive interference almost everywhere, which only switches over into constructive interference when the centers nearly coincide. An assumption needed for further development of this theory is that interaction is contingent on the development of expansive constructive interference. 

The common presence of  accelerations in our universe combined with a finite speed of light might suggest that expansive wave functions would quickly fill up with incoherence, destroying their usefulness as explanatory causes. However, if there are no non-expansive elementary particles, we just have expansive interacting with expansive to produce every acceleration. Once you get entirely away from the tiny-electron idea, it is not at all clear that any incoherence could ever develop. Such may well occur to a limited extent under some conditions, however. Relativity theory may be based on such limited incoherencies.

Two baffling kinds of experiment seem amenable to the big-electron treatment: diffraction of "particles" of matter like electrons, and entanglement experiments.

Electrons fired in a vacuum at a pair of closely-spaced slits, with a photographic plate situated on the other side of the slits, will produce a diffraction pattern on the developed plate consisting of alternating exposed and unexposed bands. These are interpreted as locations of constructive and destructive interference between "matter waves" emanating from the two slits under the stimulation of the electron beam. If the intensity of the beam is lowered to the point where only one electron is "in the chamber" at a time, thereby eliminating the possibility of inter-electron interactions inside the chamber, the diffraction pattern develops just as before. It merely takes longer. All this could happen only if each electron goes through both slits at once. This is weird if we try to use the traditional tiny-electron picture, but much easier to visualize using the big-electron picture.

Entanglement of two particles that persists over distances measured in kilometers is also easier to understand if we remember that the experimental apparatus is itself made up of expansive wave functions and is therefore mostly overlapped with the two particles being studied throughout the experiment.

If all this is true, we live in a vast web of inter-validating illusions called the particle model.

Sunday, June 18, 2017

#31. Climate Change [engineering]


Red, theory; black, fact




Reading "Just Cool It!" by Suzuki and Hanington introduced me to the ancient terra preta agricultural technology, given as a possible solution, or part of the solution, to the global warming problem. The term is apparently Portuguese for "black earth" and the technology involves enriching the soil by ploughing it full of charcoal. Suzuki and Hanington make the point that this should sequester a lot of carbon in the soil, thereby taking it out of the atmosphere. Charcoal is nearly pure carbon. Moreover, charcoal, being indigestible to decay organisms, should stay in the soil for a very long time. The logical raw material for making the charcoal would be either wood from clearing the land for agriculture, or crop residues, the parts of the crop plant that people cannot eat.

In modern pyrolysis plants, not only is charcoal produced, but also flammable off-gasses, which could be used for fuel directly in some future scenario, or catalytically reformed to a liquid fuel for running the tractors and combines. In gaseous form, the fuel could run a steam turbine to produce electricity to supplement that from wind farms, hydro, tidal, geothermal, thorium-nuclear, and photovoltaics.

However, the off-gasses are also used to fuel the pyrolysis plant itself. Whether any would be left over for other uses would depend on careful plant design for energy efficiency and on avoiding fuelled drying operations. Thus, the feedstock should be sun-dried.

Schemes like second-generation power ethanol are touted as carbon-neutral, but in terra preta with these additions, we have one that is actually carbon-negative.

However, the soil ends up black. No other color is as efficient at converting sunlight into heat, which we don't need more of at this point. This seems to be a problem with the terra preta solution. (The ideal color for avoiding heat production would be white.)

The use of any terrestrial artificial mirror membrane has the drawback that the membrane will get dirty rapidly from dust, pollen, and plant parts, thereby reducing its efficiently. However, a living means of light reflection, like a low understorey of white, downy plants, would renew itself, gratis, each year. Orbiting space mirrors have also been proposed as the solution to global warming. They wouldn't get covered in debris anytime soon -- just shot full of holes by micrometeorites.

Monday, June 5, 2017

#30. The Russian-dolls--multiverse Part II [physics]

PH

Red, theory; black, fact




Leptons may arise as electromagnetic wave functions originating in p2 that are transported into our p3 universe/condensate by ordinary diffusion and convection. Wave functions in p2 that are already leptons become our baryons when they are transported in. The only kind of wave functions that are "native" to a given frame of reference are electromagnetic (photonic) in that frame of reference. If they subsequently propagate towards increasing p (inwards) they gain mass as matter; if they propagate towards decreasing p (outwards), they first lose mass as matter until they are photonic (i.e., massless) and then gain mass as antimatter.

This scenario gives rise to previously unconsidered solutions to outstanding problems in cosmology. For example, dark matter could be just excess electrons that lack protons with which to bind. You would have to argue that we don't see them because they would collectively appear as a potential that is smooth on all but galactic scales, and it is only variations in potential, aka electric fields, that cause scattering of probe particles. Such variations would be common only in neutral matter.

To produce stable leptons from in-migrating photons, the first condensates, the p2s, would have had to be rotating simultaneously about three mutually perpendicular axes, by the assumptions of two posts ago. If this is impossible for p3 physics, we have to appeal to the possibility of a different physics in p1 for any of these ideas to make sense.

A "universe" is something like an artist's canvas with a painting in progress on it. First, nature makes the blank canvas, and then, in a second stage, puts the information content on it. Consider the moon. It formed out of orbiting molten spray from the collision of two similarly-sized planetesimals. In the molten state, its self-gravity could easily round it up into a perfect sphere which could have solidified with a mostly smooth surface. Call this smooth surface the "canvas." Subsequently, the very same force of gravity would have brought down meteors to cover the surface in an elaborate pattern of craters. Call this the "painting." 

Now consider the neutronium core of a neutron star, viewed as a p4, or small universe. The tremendous energy release of the catastrophic gravitational collapse in which it forms homogenizes all the matter into pure neutrons, thought to be a superfluid. This creates the "canvas." Subsequently, matter and energy from our p3 migrate into the super fluid without enough energy release to homogenize them, producing a "painting" of leptons (our photons), baryons (our leptons), and "uberbaryons" (our baryons). Indeed, the neutron-star core is actually thought to be not pure neutronium, but neutronium containing a sprinkling of free protons and electrons (as seen in p3, of course).

Saturday, June 3, 2017

#29. The Russian-dolls--multiverse Part I [physics]


Red, theory; black, fact

A Matryoshka

That the space we live in has an absolute frame of reference, as Newton taught, and which Einstein taught against. This frame of reference is a condensate, like the water that a fish swims in.

The divide-and-conquer strategy that has served science so well thus far can blithely continue with the conceptual disassembly of this space into its constituent particles. The question arises if these particles are situated in yet another space, older and larger than ours, or if we go direct to spacelessness, where entities have to be treated like Platonic forms. In the former case, does that older, larger space in turn comes apart into particles situated in a still older and larger, etc, etc, ad infinitum.

Infinities are the death of theories. Nevertheless, let us hold our noses and continue with the Russian-dolls idea, merely assuming that the nesting sequence is not infinite and will not be infinite until the entire multi verse is infinitely old, because the "dolls" form one by one, by ordinary gravitational collapse, from the outside in.

Wave functions would be the basic building blocks, following quantum mechanics. In the outermost space, previously called #, the wave crests always move at exactly the speed of light.

This speed is not necessarily our speed of light, c, but more likely some vastly greater value.

The space-forming particles of # are themselves aggregates with enough internal entropy to represent integers and enough secondary valences to form links to a set of nearest neighbors to produce a network that is a space. This space acts like a cellular automaton, with signals passing over the links to change the values of the stored integers in some orderly way. The wave functions are the stereotyped, stable figures that spontaneously develop in the automaton out of the initial noise mass left over from catastrophic gravitational collapse. 

The dimensionality of a space increases steadily over time, suggesting that the number of links emanating from each node in the underlying network increases slowly but surely. Macroscopically, this dimensionality increase could look something like protein folding. 

Let us label the Russian-dolls universes from the outside in, in the sequence 1, 2, 3,...etc, and call this number the "pupacity" of a given frame of reference. (From the Latin "pupa," meaning "doll.") Let us further shorten "pupacity" to "p" for symbol-compounding purposes. Thus, the consecutively labelled spaces can be referred to as p1 (formerly "#"), p2, p3,... etc.

pn can exhibit global motions ("n" is some arbitrary pupacity), such as rotation, in the frame of reference of p(n-1): a whole universe rotating as a rigid unit. Probably, it can drift and vibrate as well.

Global motions must be subtracted from the true, outer, speed-of-light speed of the wave crest to produce its apparent speed and direction when seen from within pn. Thus, the universe's love of spinning and orbiting systems of all sizes is explained: a spinning, global-motion vector is being subtracted from the non-spinning, outermost one. As the pupacity of the frame of reference increases, more and more of these global vectors are being subtracted, causing the residual apparent motion to get progressively smaller. We would assume under current physics that the wave functions are acquiring more and more mass, to make them go slower and slower, but mass is just a fiction in this scenario. However, the reliance of current physics on the mass construct is an opportunity to determine the pupacity of planet Earth: it is three.

Three, because physics describes three broad categories of particle mass: the photon, leptons, and baryons. The photon would be native to p1, leptons, such as electrons and positrons, would be native to p2, and baryons, such as protons and neutrons, would be native to p3, our own sub-world. 

The positron atom would be a standing-wave pattern made up of oppositely rotating wave functions, an electron and a positron, both native to p2. A neutron would be exactly the same thing, but native to p3. 


Wednesday, May 31, 2017

#28. My Second Theory of Everything [physics]


Red, theory; black, fact



How does wavelike, low-frequency light becomes particle-like, high-frequency light as frequency is smoothly increased? Waves are continuous, whereas particles are discontinuous; how, then, does the breakup occur?

You have to put the source in the picture. Recoil of the source atom sends the wave function off in a specific direction, but the wave function is known to expand (about its center of symmetry?) as it goes. Presumably, it is the vector sum of these two motions that must equal the speed of light; either one is presumably free to take on some lower speed, say, that of a pitched softball. I conjecture that as frequency increases, the particle-like drift of the center progressively dominates the mixture at the expense of the local, wave-like expansion of the wave function about its center. This is how I see waves morphing into particles as the frequency increases. 
  • There is an absolute frame-of-reference, #.
  • All motions seen in this frame of reference will be observed to occur at the speed of light (c); and only this frame of reference has this property.
  • All speeds lower than c are illusions caused by the motion of the observer's frame of reference.
  • That which moves always at c is not a wave function, but a phase marker of some sort within it, such as a zero crossing or a wave crest.
  • The local wave function evolution relative to its center of symmetry combined with the drift of that center relative to # always travels at c relative to #.
  • If local evolution is an expansion along all wave function radii, you have light; if it is a rotation about the center of symmetry (i.e., motion perpendicular to radii), you have matter.
  • Light wave functions will be like nested spherical shells, whereas matter wave functions will have a lobar, angle-dependent structure like a p-, d-, or f-orbital in theoretical chemistry. The lobes are essential to provide a contrast pattern that could, in principle, be observed to spin.
  • The presence of one axis of rotation produces the neutrino; two simultaneous axes of rotation produce the mesons; three produce the remaining stable particles, e, p, and n. If the three rotational rates are distinguishable, the resulting structure has a handedness.
  • The matter/antimatter dichotomy arises from this handedness, when combined with a law of conservation of spin that would result from space initially being symmetrical. 
  • The mesons should have an ability in 3-space to flip over into their corresponding antiparticles.

Friday, May 19, 2017

#27. The Origin of Consciousness [neuroscience]


Red, theory; black, fact




We begin life conscious only of our own emotions. Then the process of classical conditioning, first studied in animals, brings more and more of our environment into the circle of our consciousness, causing the contents of consciousness to become enriched in spatial and temporal detail. Thus, you are now able to be conscious of these words of mine on the screen. However, each stroke of each letter of each word of mine that now reaches your consciousness does so because, subjectively, it is "made of" pure emotion, and that emotion is yours.

Some analogies come to mind. Emotion as the molten tin that the typesetter pours into the mold, the casting process being classical conditioning and the copy the environmental data reported by our sense organs. Emotion as the bulk on one side of a fractal line and sensory data the bulk on the other side. Emotion as an intricately ramifying tree-like structure by which sensory details can send excitation down to the hypothalamus at the root and thus enter consciousness.

The status of "in consciousness" can in principle affect the cerebral cortex via the projections to cortex from the histaminergic tuberomamillary nucleus of the hypothalamus. Histamine is known to have an alerting effect on cortex, but to call it "alerting" may be to grossly undersell its significance. It may carry a consolidation signal  for declarative, episodic, and flash memory. Not for a second do I suppose all of that to be packed into the hippocampus, rather than being located in the only logical place for it: the vast expanse of the human cerebral cortex.

Monday, April 3, 2017

#26. Why Organized Religion? Theory Two [evolutionary psychology]


Red, theory; black, fact




Emotions are an "endophenotype," a term from functional magnetic resonance imaging, that provides a useful stepping stone from evolutionary arguments to explanations of our daily lives. 

What is the mood or feel as you enter a place of worship and participate in the ceremonies conducted there? More than anything else, the mood is one of great reverence, as though one is in the presence of the world's most powerful king. Kings are supposed to "represent their race." Problem: if the emotional outlines of people's behavior is being partly randomized in each generation by recombination-type mutations, a consistent moral code seems impossible if we assume that morality comes mostly from peoples' inborn patterns of emotional reactivity, that is, the sum total of everyones' preferences. The purpose of a king may be to find or at least coincide with societies' moral center of gravity, around which a formal, if temporary, moral code can be constructed. In a complex society, everyone must be "on the same page" for efficient interaction. 

The same problem no doubt recurs each time organisms come together to form a colony, or super-organism: the conflict between the need of a colony for coordination of colonists and the need of evolution for random variability. Such variability will inevitably affect the formulation and interpretation of the coordinating messages that the colonists exchange, like all their other inborn characteristics. 

With kingship comes the corrupting influence of personal power and  tyrannical government. Replacing a real king with a pretend-king named "God" would seem to be the solution that accounts for organized religion, but then one loses the flexibility that goes with having a flesh-and-blood king who can change his predecessor's laws based on current popular sentiment.

However, human nature may well have a core-and-shell structure, with an "unchanging" core surrounded by a slowly changing shell. The former would be the species-specific objective function previously alluded to in post #16, and produced by species-replacement group selection within the genus, and the latter would be due to PNS, and would represent the stratagems hit upon by our ancestors to meet the demands of the objective function in our time and place. This shell part may account for cultural differences between countries. The core may be implemented in the hypothalamus of the brain, whereas the shell may be implemented in the limbic system. The core, being unchanging, could be taught by organized religion, whereas the shell could be codified by the more flexible institution of government. Though the core is unchanging overall, specific individuals will harbor variations in it due to point mutations (not part of PNS), necessitating the standardizing role of religion. Synaptic plasticity would then be used to cancel the point-mutational variation in the objective function.

This core  consists of four pillars, or themes: genetic diversity, memetic diversity, altruism, and dispersal. Our energetic investment in obtaining each item is to be optimized. To produce this, the church of my acquaintance is continually emphasizing, respectively, tolerance, creating beautiful things, charity, and justice. 

Wednesday, March 29, 2017

#25. The Phasiverse [physics]


Red, theory; black, fact

The nucleus around which a theory of everything will hopefully crystallize.


Our reality, the world of appearances, is encoded in the relative phases of tan ineffably large number of oscillators, each of which is a kind of primitive clock.

An early interpretation of the theory of quantum mechanics was that there is a harmonic oscillator somehow assigned to each point in space, and that these account for the matter fields of the universe. Examples of such oscillators would be masses bouncing up and down on springs, and electronic devices called tank circuits, which are just one capacitor connected across the terminals of one inductor. 

If a set of such oscillators can communicate with each other (exchange oscillatory energy), this is called coupling, and it can make the oscillators tend to pull each other in to the same, common phase. The Huygens's clocks experiment begins with two old-school pendulum clocks in a case with their pendulums swinging in some random phase relationship. The next day, mysteriously, the pendulums will always be found swinging in opposite directions. The coupling is evidently due to tiny, rhythmic forces travelling through the common case from clock to clock.

If the coupling is positive, as assumed here, (it's negative in the above experiment), the phase pull-in effect becomes stronger the closer the two phases approach each other, causing a positive feedback effect. This is very reminiscent of Hebb's rule in neuroscience and the tendency of natural attractive forces such as gravity to depend inversely on distance. 

The phase pull-in effect provides a simple answer to questions such as where the organizing principle comes from. All you need to explain is where the oscillators themselves all came from, how they oscillate, and why they are coupled. Since the oscillators begin life in spacelessness, they cannot avoid interacting to produce a coupling effect. Second, oscillators need no past or future; they can arise as a succession of causally related nows that alternates between two contrasting forms. Figures in Conway's game of Life would seem to be examples of this alternation.

A great many oscillators all with the same phase is not an interesting universe. However, suppose this is impossible because of "train wrecks" happening during the synchronization process that produce frustration of the synchronization analogous to spin frustration in spin glasses. An example would be a cyclic relationship of oscillators in which a wave goes around the loop endlessly. Such cycles may correspond to particles of matter in our universe, and the spiral waves that they would throw off into surrounding space may correspond to the fields around such particles.

A black hole or galaxy would be surrounded by a tremendous number of such radiating fields. The resulting desychronization of the oscillators making up the surrounding space would increase the average phase difference between phasically nearby oscillators, thereby inhibiting their coupling, thereby inhibiting the travel of signals generally through the region. Result: the speed of light is reduced in the vicinity, resulting in the bending of light rays, called gravitational lensing. 

Quantization could be due to the presence of small quantities comparable in size to the value of the least significant bit of an integer-like entity.

Sunday, March 26, 2017

#24. Proxy Natural Selection from the Inside [evolutionary psychology, genetics]

EP   GE

Red, theory; black, fact



My first post on post-zygotic gamete selection (PGS) left open some questions, such as what it should feel like, if anything, when one is fulfilling the species objective function and being deemed "proxy-fit" by one's own hypothalamus.

I conclude that it's just what you would think: you feel joy and/or serenity. Joy is one of Ekman's six basic universal human emotions, the others being fear, anger, disgust, sadness, and surprise. I think that emotions collectively are the operations of the highest-level human behavioral program. (That is, the program in its broadest outlines.) The unpleasant emotions force you to get off the couch until they are taken care of, and joy lets you get back on. Thus, the unpleasant four are the starting emotions, and joy is the stopping emotion. 

Surprise may be a meta-emotion that tells you that your threshold for experiencing one of the other emotions is too high, and immediately lowers it. Each activation of an emotion may tend to lower the threshold for activating it next time, which implies a positive feedback loop capable of changing the personality to suit suddenly changed circumstances, especially if the emotion eventually begins issuing with no trigger at all.

To relate this to the mechanism of PGS, the crossing-over events that went into making the sperm cell that made a given person would theoretically affect brain development more than anything else, specifically connecting some random stimulus to one of the unpleasant primary emotions. This creates temperament, and thus  personality, which is the unique quality which they have to offer the world, and on which they are being tested by history. If the actions to which their own, special preferences propel them are what the species objective function is looking for, they succeed, feel joy and serenity, and experience an altered methylation status of the DNA in the spermatogonia if male, which suppresses further crossing over in the manufacture of sperm, so that their personality type breeds true, which is what the population needs. 

PGS is quick evolution to respond to challenges that come and go on less than a multi-thousand generation timescale, and it explains the complexities of sexual reproduction. However, trees have no behavior, much less personalities, and yet they have sexual reproduction. However, trees probably adapt quickly not by behavioral change, but by changes in their chemistry. The chemistry in question would be the synthesis of pesticidal mixtures located in the central vacuole of each plant cell. In terms of such mixtures, each tree should be slightly unique, an easily testable prediction.

Each of the four unpleasant "starting" emotions may sub serve one of the four pillars of the species objective function. Thus: sadness, altruism; disgust, genetic diversity (due to point mutations; what is motivated here is the screening of such novelties, screening always being the expensive part); fear, memetic diversity (or motivating prescreening of memetic novelties); anger, dispersal. Each of these emotions seems to have another use, in preserving the life of the individual, as opposed to the entire species. Thus: sadness, unfavorable energy balance; disgust, steering one away from concentrations of harmful bacteria; fear, avoidance of injury and death; anger, driving away competitors for food and mates. 

Sunday, February 12, 2017

#23. The Pictures in Your Head [neuroscience]


Red, theory; black, fact




My post on the thalamus suggests that in thinking about the brain, we should maintain a sharp distinction between temporal information (signals most usefully plotted against time) and spatial information (signals most usefully plotted against space). Remember that the theory of General Relativity, which posits a unified space-time, applies only to energy and distance scales far from the quotidian.

In the thalamus post, I theorized about how the brain could tremendously data-compress temporal information using the Laplace transform, by which a continuous time function, classically containing an infinite number of points, can be re-represented as a mere handful of summarizing points called poles and zeroes, scattered on a two-dimensional plot called the complex frequency plane. Infinity down to a handful. Pretty good data compression, I'd say. The brain will tend to evolve data-compression schemes if these reduce the number of neurons needed for processing (I hereby assume that they always do), because neurons are metabolically expensive to maintain and evolution favors parsimony in the use of metabolic energy.

Ultimately, the efficiency of the Laplace transform seems to come from the fact that naturally-occurring time functions tend to be pretty stereotyped and repetitious: a branch nodding in the wind, leaves on it oscillating independently and more rapidly, the whole performance decaying exponentially to stillness with each calming of the wind; an iceberg calving discontinuously into the sea; astronomical cycles of perfect regularity; and a bacterial population growing exponentially, then shifting gears to a regime of ever-slowing growth as resources become limiting, the whole sequence following what is called a logistic curve.

Nature is very often described by differential equations, such as Maxwell's equations, those of General Relativity, and Schrodinger's Equation, the three greats. Other differential equations describe growth and decay processes, oscillations, diffusion, and passive but non-chemically energy-storing electrical and mechanical systems. A differential equation is one that contains at least one symbol representing the rate of change of a first variable versus a second variable. Moreover, differential equations seem to be relatively easy to derive from theories. The challenge is to solve the equation, not for a single number, but for a whole function that gives the actual value of the first variable versus the second variable, for purposes of making quantitative, testable predictions, thereby allowing testing of the theory itself. The Laplace transform greatly facilitates the solution of many of science's temporal differential equations, and these solutions are remarkably few and stereotyped: oscillations, growth/decay curves, and simple sums, magnifications, and/or products of these. Clearly, the complexity of the world comes not from its temporal information, but from it's spatial information. However, spatial regularities that might be exploited for spatial data compression are weaker than in the temporal case.

The main regularity in the spatial domain seems to be hierarchical clustering. For an example of this, let's return to the nodding branch. Petioles, veins, and teeth cluster to form a leaf. Leaves and twigs cluster to form a branch. Branches and trunk cluster to form a tree. Trees cluster to form a forest. This spatially clustered aspect of reality is being exploited currently in an approach to machine intelligence called "deep learning," where the successive stages in the hierarchy of the data are learned by successive hidden layers of simulated neurons in a neural net. Data is processed as it passes through the stack of layers, with successive layers learning to recognize successively larger clusters, representing these to the next layer as symbols simplified to aid further cluster recognition. This technology is based on discoveries about how the mammalian visual system operates. (For the seminal paper in the latter field, see Hubel and Wiesel, Journal of Physiology, 1959, 148[3], pp 574-591.)

Visual information passes successively through visual areas Brodmann 17, 18, and 19, with receptive fields becoming progressively larger and more complex, as would be expected from a hierarchical process of cluster recognition. The latter two areas, 18 and 19, are classed as association cortex, of which humans have the greatest amount of any primate. However, cluster recognition requires the use of neuron specialist sub-types, each looking for a very particular stimulus. To even cover most of the cluster-type possibilities, a large number of different specialists must be trained up. This does not seem like very good data compression from the standpoint of metabolic cost savings. Thus, the evolution of better ability with spatial information should require many more new neurons than with the case of temporal information.

My hypothesis here is that what is conferred by the comparatively large human cerebral cortex, especially the association cortices, is not general intelligence, but facility with using spatial information. We take it on and disgorge it like water-bombers. Think of a rock-climber sizing up a cliff face. Think of an architect, engineer, tool-and-die maker, or trades person reading a blueprint. Now look around you. Do we not have all these nice buildings to live and work in? Can any other animal claim as much? My hypothesis seems obvious when you look at it this way.

Mere possession of a well developed sense of vision will not necessarily confer such ability with spatial information. The eyes of a predatory bird, for instance, could simply be gathering mainly temporal information modulated onto light, and used as a servo error for dynamically homing in on prey. To make a difference, the spatial information has to have someplace to go when it reaches the higher brain. Conversely, our sense of hearing is far from useless in providing spatial information. We possess an elaborate network of brain-stem auditory centers for accomplishing exactly this. Clearly, the spatial/temporal issue is largely dissociable from the issue of sensory modality.

You may argue that the uniquely human power of language suggests that our cortical advantage is used for processing temporal information, because speech is a spaceless phenomenon that unfolds only in time. However, the leading theory of speech seems to be the Wittgenstein picture theory of meaning, which postulates that a statement shows its meaning by its logical structure. Bottom line: language as currently understood is entirely consistent with my hypothesis that humans are specialized for processing spatial information.

Since fossil and comparative evidence suggests that our large brain is our most recently evolved attribute, it is safe to suppose that it may be evolving still, for all we know. There may still be a huge existential premium on possession of improved spatial ability. For example, Napoleon's strategy for winning the decisive Battle of Austerlitz while badly outnumbered seems to have involved a lot of visualization. The cultural face of the zeitgeist may reflect this in shows and movies where the hero prevails as a result of superior use of spatial information. (e.g., Star Wars, Back to the Future, and many Warner Bros. cartoons). Many if not most of our competitive games take place on fields, courts, or boards, showing that they test the spatial abilities of the contestants. By now, the enterprising reader will be thinking, "All I have to do is emphasize the spatial [whatever that means], and I'll be a winner! What a great take-home!"

Let me know how it goes, because all this is just theory.

Monday, February 6, 2017

#22. Proxy Natural Selection: The God-shaped Gap at the Heart of Biology [genetics, evolution]

EV   GE

Red, theory; black, fact



Some entity must be responsible for compensating for the fact that our microbial, insect, and rodent competitors evolve much faster than we do because of their shorter generation times. In these pages, I have been variously calling this entity the intermind, the collective unconscious, the mover of the zeitgeist, and the real, investigable system that the word "God" points to. I here recant my former belief that epigenetic marks are likely to be the basis of an information storage system sufficient to support an independent evolution-like process. I will assume that the new system, "post-zygotic gamete selection" (PGS) is DNA-based.

First, a refresher on how standard natural selection works. DNA undergoes various mutations that add diversity to the genome. The developmental process translates the various genotypes into a somewhat diverse set of phenotypes. Existential selection then ensues from the interaction of these phenotypes with the environment, made chronically stringent by population pressure. Differential reproduction of phenotypes then occurs, leading to changes in gene frequencies in the population gene pool. Such changes are the essence of evolution.

PGS assumes that the genome contains special if-then rules, perhaps implemented as cis-control-element/structural gene partnerships, that collectively simulate the presence of an objective function that dictates the desiderata of survival and replaces or stands in for existential selection. A given objective function is species-specific but has a generic resemblance across the species of a genus. The genus-averaged objective function evolves by species-replacement group selection, and can thus theoretically produce altruism between individuals. The if-then rules instruct the wiring of the hypothalamus during development, which thereby comes to dictate the organism's likes and dislikes in a way leading to species survival as well as (usually) individual survival. Routinely, however, some specific individuals end up sacrificed for the benefit of the species.

Crossing-over mutations during meiosis to produce sperm increase the diversity of the recombinotypes making up the sperm population. During subsequent fertilization and brain development, each recombinotype instructs a particular behavioral temperament, or idiosyncratotype. Temperament is assumed to be a set of if-then rules connecting certain experiences with the triggering of specific emotions. An emotion is a high-level, but in some ways stereotyped, motor command, the details of which are to be fleshed out during conscious planning before anything emerges as overt behavior. Each idiosyncratotype interacts with the environment and the result is proxy-evaluated by the hypothalamus to produce a proxy-fitness (p-fitness) measurement. The measurement is translated into blood-borne factors that travel from the brain to the gonads where they activate cell-surface receptors on the spermatogonia. Good p-fitness results in the recombination hot spots of the spermatogonia being stabilized, whereas poor p-fitness results in their further destabilization. 

Thus, good p-fitness leads to good penetrance of the paternal recombinotype into viable sperm, whereas poor p-fitness leads to poor penetrance, because of many further crossing-over events. Changes in hotspot activity could possibly be due to changes in cytosine methylation status. The result is within-lifetime changes in idiosyncratotype frequencies in the population, leading to changes in the gross behavior of the population in a way that favors species survival in the face of environmental fluctuations on an oligo-generational timescale. On such a timescale, neither standard natural selection nor synapse-based learning systems are serviceable.

The female version of crossing over may set up a slow, random process of recombination that works in the background to gradually erase any improbable statistical distribution of recombinotypes that is not being actively maintained by PGS.

A better theory of female PGS 

First, a definition. PGS focus: a function that is the target of most PGS. Thus, in trees, the PGS focus is bio elaboration of natural pesticides. In human males, the PGS focus is brain development and the broad outlines of emotional reactivity, and thus behavior. In human females, the PGS focus is the digestive process. The effectiveness of the latter could be evaluated while the female fetus is still in the womb, when the eggs are developing. The proxy fitness measure would be how well nourished the fetus is, which requires no sensory experience. This explains the developmental timing difference between oogenesis and spermatogenesis. Digestion would be fine tuned by the females for whatever types of food happen to be available in a given time and place.

Experimental evidence for the proposed recombination mechanism of PGS has been available since 2011, as follows:
Stress-induced recombination and the mechanism of evolvability
by Weihao Zhong; Nicholas K. Priest
Behavioral Ecology and Sociobiology, 03/2011, Volume 65, Issue 3
Abstract:
"The concept of evolvability is controversial. To some, it is simply a measure of the standing genetic variation in a population and can be captured by the narrow-sense heritability (h2). To others, evolvability refers to the capacity to generate heritable phenotypic variation. Many scientists, including Darwin, have argued that environmental variation can generate heritable phenotypic variation. However, their theories have been difficult to test.
 Recent theory on the evolution of sex and recombination provides a much simpler framework for evaluating evolvability. It shows that modifiers of recombination can increase in prevalence whenever low fitness individuals produce proportionately more recombinant offspring. Because recombination can generate heritable variation, stress-induced recombination might be a plausible mechanism of evolvability if populations exhibit a negative relationship between fitness and recombination. Here we use the fruit fly, Drosophila melanogaster, to test for this relationship.
We exposed females to mating stress, heat shock or cold shock and measured the temporary changes that occurred in reproductive output and the rate of chromosomal recombination. We found that each stress treatment increased the rate of recombination and that heat shock, but not mating stress or cold shock, generated a negative relationship between reproductive output and recombination rate. The negative relationship was absent in the low-stress controls, which suggests that fitness and recombination may only be associated under stressful conditions. Taken together, these findings suggest that stress-induced recombination might be a mechanism of evolvability."

However, my theory also has a macro aspect, namely that the definition of what constitutes "stress," in terms of neuron interconnections or chemical signaling pathways, itself  evolves, by species-replacement group selection. 

Friday, January 27, 2017

#21. The Cogs of Armageddon [evolutionary psychology]


Red, theory; black, fact




How does everyday human behavior eventually accomplish the biological function of dispersal for the human race? 

Dispersal is things like dandelions shedding airborne seeds, slime molds developing into spore cases on stalks and releasing the spores into the wind, territorial systems of birds and mammals forcing the unlanded young to seek widely for their own territories, and humans going into space because our science fiction writers keep scaring us about the possibility of meteor crashes wiping out life on Earth. 

The slime mold Dictyostelium is triggered into its dispersal program by the food supply running short; I will adopt the assumption that the human dispersal program is also triggered by the end of the good times, that is, the price of bread rising relative to wages.

Human neural pathways may potentiate aggression when the hard times come, but of an elaborate kind adapted for ensuring efficient dispersal (i.e., with minimal loss of life). It begins with a two-person feud of the sort illustrated in cultural references too numerous to mention. An arbitrary stimulus, made offensive by some piece of Pavlovian conditioning, is traded back and forth with rapidly increasing energy. 

The emotional component is strongly threatening because the participants must be induced to seek allies, which people do when threatened, until all of society is eventually polarized. The acts of provocation being traded back and forth become progressively more outrageous, as they must, to keep the polarization process going. Eventually, one side gets the upper hand and forces the other to flee.

The result is a diaspora, i.e., dispersal. Because of the long polarization process, an entire group is expelled, not single individuals one at a time. Thus, members of such a group can assist each other to survive and relocate, thereby reducing the mortality associated with dispersal, thereby making the dispersal event more efficient in terms of number of people relocated. The group who flees is then seen by the international community as the blameless victim, and the group who stays is seen as the unprincipled aggressor. This tends to elicit a sheltering of the refugees and an intimidation of the "aggressor," who is deterred from pressing his advantage, that is, pursuing the refugees and slaughtering them to the last man, which is what each side would like to do to the other by this point. This, again, is an efficiency from the point of view of producing dispersal.

However, if each side is continually threatening the other, why don't they flee each other's presence during the very early stages? Humans may have a reflex that converts feeling threatened into a wish to injure the threatening party, possibly a behavioral leftover from some earlier adaptation, such as an anti-predation defense; to injure, you have to stick around. 

Finally, settled refugees usually do not integrate completely into the host society, instead forming ethnic neighborhoods. Being seen as ethnic by the host society, due to slow integration, could improve the reproductive success of refugees because of disassortative mate-choice effects evolved to favor genes that produce dispersal.

The dispersal-producing dynamic just outlined is powerful, because it must overcome all the reasons a person would not leave their homeland forever at some arbitrary time: expense, risk of mortality in transit, opportunity costs, temporary loss of livelihood, need to learn a new language and customs, vulnerability to exploitation in the new country, etc.