Thursday, June 13, 2019

#54. Reality is Virtual but the Host Computer is Analog. [physics, chemistry, neuroscience]


Red, theory; black, fact.
The nucleus around which a TOE will hopefully crystallize.


Here is my idea of what lies behind the veil of space time: something like a Turing machine, but with a multiplicity of tapes and a multiplicity of processors. Each tape corresponds to one elementary particle in space time and the processors implement only Hebb’s rule, a rule of learning first discovered in neuroscience, and that governs correlations among signal sources. The tapes are polymer-like, and their ongoing elongation by polymerization at the ends causes the passage of time. This elongation is associated with a white-noise signal unique to each particle/tape/strand because the monomers are sampled from a population with a Gaussian size distribution.
06-26-2019: A theoretical schema showing the basic strand-processor interaction. The theory borrows from the Turing machine concept, Hebb's rule of learning, and the chemistry of polymerization. Black, one information-bearing polymer strand; blue, processor; red, monomers.
07-03-2019: A more complex, two-strand scheme. The monomer cloud has been omitted for clarity.
07-09-2019: A still more complex, three-strand
scheme. Assumption: at a given point, multiple strands can adhere to the same processor, and vice-versa.

06-26-2019: The first illustration is my current best guess as to what a "Hebb processor" is like, but as we say, "Many questions remain." The short, black lines are the catalyzed ligation points between "monomers," and these are the points of attraction to the processor. If the rear pull-off point encounters a big gap between ligation points, the processor will advance an unusually great distance in one step, creating an unusually long catalytic pocket at the front, which will have a selectivity for longer monomers, thereby implementing a copying mechanism. (Causally, this is backwards, but the alternative seems to involve a messy discussion of chemical equilibria.)

This “machine” is presumed to be naturally occurring and to belong to a particular stage in the physical evolution of the universe. (i.e., I make no appeal to arguments of intelligent design, even by space aliens.) By the anthropic principle, the machine is not necessarily typical of all structures extant at that stage. <06-04-2020: In other words, we are living in a natural subworld that is simulation-like in that the view from within is entirely unlike the view from without, but the two views are lawfully related by something that could be called the "subworld law," an example of which is given below, i.e., "d = K/rxy." (This concept is nothing new because it could also serve in outline as a description of human conscious experience, which is most unlike a mass of neurons signaling to each other in the dark.) Thus, the Theory of Everything could turn out to be a series of nested subworld laws.>

The length of a strand relative to some interior point is a Gaussian white-noise time-series signal with an upward trend just steep enough to eliminate negative slopes. I will deal here with the detrended version of this signal because, on the laboratory distance scale, both the observed system and the observer will share the same trend, preventing its direct observation. Moreover, the polymerization process is postulated to preserve a permanent record of the detrended signal. Therefore, while the future does not exist in this model of time, the past is perfectly preserved. A set of distinguishable time series is called “panel data” and is a Euclidean space by the mathematical definition and can therefore map onto and explain physical space, at least on the laboratory scale.

Imagine some panel data consisting of two time series, X and Y, representing two elementary particles. Take a slice of this data ten samples long and plot them as two ten-dimensional vectors, X and Y. The dot product of these vectors is then easily computed as x₁y₁ + x₂y₂ + … x₁₀y₁₀. A Euclidean space is defined as an affine space (i.e., containing no special points like the origin) where the vector dot product is defined. Recall that this dot product is equal to the length of X times the length of Y times cosθ, where θ is the angle between the vectors. Moreover, cosθ is here equal to rₓy, aka Pearson’s r, a measure of correlation between signal sources. Pearson's r is commonly used in the sciences, including neuroscience, and ranges from -1 for negative correlations to +1 for positive correlations; zero indicates no correlation.

I conjecture that rxy represents distance in space time, and vector length represents mass-energy in space time. An rxy of 0 would represent infinite distance and an rxy of 1 would represent 0 distance, a state found only in black-hole singularities or the big bang singularity. Processes would be experienced as close together because they are correlated  (Previously suggested in Post #4.), not correlated because they are close together. The latter is the usual assumption, usually rationalized as being due to the easy exchange of synchronizing photons or virtual photons at close range. However, we seem to be moving here toward the elimination of the light/photon construct from physics. Good riddance; it was always pretty dicey.

(Deprecated, Part 6)
07-25-2015 to 07-27-2019: A simpler possibility is d = K/rxy and rxy = K/d. This change advantageously limits how small space-time distances can become, thereby eliminating infinities from gravity calculations. K is this minimum length. With this revision, the dot product of two vectors in the simulation becomes equal to gravitational binding energy.

No Flying Spaghetti Monster would be complete without meatballs, and these would be the Hebb processors alluded to in the opening paragraph. Each strand would have a processor on each end that may catalyze the polymerization process. Each processor would also be connected to a random point within the mass of strands. This connection moves along the associated strand like a phonograph needle,  reading the recorded signal while keeping pace with the growing end. The processor also has a front read-point in the present. The two read points may or may not be on the same strand. If a correlation is detected between the two read points, the correlation is permanently enhanced by a modification of the polymerization process, per Hebb’s rule. All the orderliness of the universe is supposed to emerge from this one type of calculation.

07-9-2019: At this point, we have not eliminated "space" from physics; we have merely replaced Euclidean space by another kind of space that is less structured, in which the "spaghetti machine" has its being. The new space is a "metric space" but has neither norm nor dot product axiomatically, although they can be present in simulation.The metric is bijective with the counting (natural) numbers and is equal to the number of "primordial time elements" (PTEs) in a polymer of same.

Degrees of correlation less than maximal are encoded in the processor as the number of strands adhering to the processor above the minimum for inter strand copying, namely two. One of these "middle strands," as I shall call them, is illustrated in the sketch of the three-strand scheme, and they putatively degrade the fidelity of the copying process and reduce Pearson's r in proportion to their numbers, while also introducing a time delay into the copying process, due to changes in the length of the processor. A reduction in Pearson's r, which increases the encoded space time distance, simultaneous with an increase in the copying time delay is responsible for the finite speed of light.

7-15-2019: If N is the number of middle strands on a processor, then a reasonable guess as to its effect on Pearson’s r would be r = 1/(N + 1). (Deprecated, Part 6) 07-22-2019: slight problem: the units analysis doesn't work out, so this paragraph is a work in progress.
07-25-2019: The problem is solved if we set the electron binding energy equal to the length of the projection of the electron vector on the proton vector. This is not the dot product and it has the correct units, namely mass-energy. The revised attempt to reproduce Rydberg's formula is:
ΔE = ||e||*(1/n₁ – 1/n₂), n₂ > n₁. (1)

The default interaction implemented by Hebb’s rule would be gravitational attraction. Black hole formation illustrates that gravitation has a built-in positive feedback, and this would derive from the positive feedback built into simple forms of Hebb’s rule.
07-9-2019: To provide my hypothetical Hebb processors with such a positive feedback, I postulate the following: Middle strands come and go in an energy-dependent excision/reintegration process and have a small loop of processor adhering to them when free, which explains how the processor length changes occur. A high-fidelity copying process releases more energy than does a low-fidelity copying process, and excision requires energy input. These ingredients, together with the fidelity-degrading property of a middle strand, should be sufficient for a positive feedback.
If the two read points are on the same strand, the result will be an oscillation. Electromagnetism could be the set of interactions peculiar to oscillating strands. The variance needed to express the oscillation would be deducted from a fixed total, resulting in less variance available to represent distances by its correlations. A smaller distance signal will be more rapidly modified by the Hebb processors, resulting in faster responses to forces and a smaller mass according to Newton’s a = F/m. Thus, we expect neutral particles to be more massive than charged particles, and this tendency is indeed found among the mesons and when comparing the proton and neutron. The relatively great mass of the proton and neutron and the nuclear strong force itself may emerge from a cyclic pattern of three strands (the quarks) connected by three processors. The example of the benzene molecule teaches us to expect novel results from cyclization. (07-31-2019: This will be a huge idea when asking what underlies the metric space alluded to above. 01-17-2020: The metric space may itself be a simulation running on a processor situated in a still simpler space, namely a topological space, in which only a few distinctions matter, such as inside-outside and closed-open. 01-17-2020: The great mass of the baryons may come from the chaos inevitable in the celestial-mechanics version of the three-body problem, but the three bodies would be the three quarks. Recall that in the present theory, noise amplitude corresponds to mass-energy, and fast chaos looks like noise. The three-fold nature of these particles may also create the three-dimensionality of space, but I am having trouble picturing this.

05-22-2020: An extension of this idea would be that chaos is the source of all mass and the properties of a timeline depend on how many highly-correlated others there are ("intimates") and the degree of this correlation. One intimate produces an oscillation but no mass; two or more produce chaos and some amount of mass. Intimacy can be understood as relative, leading to a hierarchy of relationships. The fact that three bodies are the minimum for chaos remains an attractive explanation for the three-dimensionality of space. Details remain elusive, but I am now trying for a holistic vision and no longer focusing narrowly on baryons.

05-22-2020: There may be an alternative kind of middle strand or mode of adhesion that enhances copying fidelity upon adhesion rather than degrading it. This amendment to the theory may be required to model interactions that appear repulsive.

Hebb processors with their rear read points in the distant past would open up long-distance communication channels in space time, giving us the by-now familiar experience of looking millions of years into the past through powerful telescopes, to see galaxies as they were when the universe was young. The communication would be instantaneous, but from an old source; not slow from a new source.

06-18-2019: The big bang:
I conjecture that the universe began in a singularity for a trivial reason: it initially had no way to represent information, let alone correlations, because all the incoming monomers were PTEs, identical in size and having the smallest possible size. A slow direct condensation reaction in the monomer pool then gradually built up larger blocks of PTEs, causing the average size of the items adding to the strands by polymerization to increase progressively. The standard deviation of the size distribution would likewise have increased. Space would have expanded rapidly at first, as predicted by the inflationary hypothesis, because the first little bit of polymerization entropy to develop would have had a disproportionate effect on the system's ability to represent information. The mass-energy of all particles has also been increasing ever since the big bang.

07-25-2019: Therefore, by equation (1), we expect that spectral lines from ancient luminous matter will be redder than comparable lines from contemporary matter, as found by Hubble, which explains the cosmological red shift.

01-17-2020: Another perspective would be that the future is a false vacuum, the past is a true vacuum, and the present is the ever-expanding boundary between. The false-vacuum decay would be driven by entropy increase, not enthalpy (i.e., heat content) decrease (which is allowed by the second law of thermodynamics), because only the interior of the true-vacuum bubble would be occupied by information (i.e., the timelines).

"I could be bounded in a nutshell and count myself a king of infinite space, were it not that I have bad dreams." Hamlet, II.ii

Thursday, May 23, 2019

#53. Advanced Human Depopulation Model [Population, Evolutionary Psychology]

Picture 1: A four-stage model of a human depopulation event. C = cycle; growth = growth phase; depop = depopulation

PO     EP     
Red, theory; black, fact


I present in Picture 1 a four-stage model of human depopulation events that is intended to account for more data. The same two emotional programs, the anger cycle and the sadness cycle (see post #41), occur in two "generations," with the second generation having greater violence and using modified signals.
  • Stage 1: depopulation by emigration; accomplishes dispersal of the human species; coordinated by an exchange of anger signals;
  • Stages 2-4: depopulation by mass murder: accomplishes long-term population density confinement within limits;
  • Stage 2: coordinated by an asymmetric exchange of contempt and sadness signals; has similarities with cannibalism;
  • Stage 3: total war program; coordinated by an exchange of anger signals with mimicry added;
  • Stage 4: loss of civilization; triggered by a repudiation of the social contract by trusted elites with grudges: coordinated by increasing paralysis on the part of victims and increasing cynicism on the part of perpetrators. May be too recent an evolutionary development to have an efficient halting signal.

Nevertheless, the modes of worship of Islam are the best place to look for such a signal (06-02-2019: or other remedy) if it exists. 

In this connection, the Islamic prayer discipline has extraordinary potential to alter brain physiology, based on variations in blood flow to this organ, known to be highly sensitive to same. The variations would come about as a result of the highly regimented posture changes occurring during Islamic prayer. I have coded these postures according to the probable effect on blood pressure measured at the brain, and the result looks like this:
Picture 2. The inferred brain physiology of Islamic prayer. Source of data: YouTube, "Time to pray with Zacky," accessed 05-23-2019.

 Shown are my inferred variations in brain oxygenation during two rakat, or units of prayer. Bowing is coded the same as sitting, namely 1. Prostration is coded as 2 and standing is coded as 0. Some forms of Islam prescribe up to 19 rakat per day. Special procedures (Sujud Sahwi) exist for fixing prayers performed erroneously due to "forgetfulness" but this "forgetfulness" I find suggestive of temporary brain dysfunction due to lack of oxygen from getting up too quickly, possibly at about minute 2, above.
06-02-2019: Unprompted revision for clarity and sensitivity: The above observation is to help establish that Islamic prayer manipulates a variable that matters, always an important issue at the outset of a research project. You don't want to waste taxpayer money blindly researching variable after variable and concluding at great expense merely that none of them was relevant.

Saturday, March 16, 2019

#51. A Theory of Christianity [Evolutionary Psychology, Population]

EP     PO     
Red, theory; black, fact.


My Christianity-inspired alcohol microdosing setup. Experimental beer dose = 44 mL/day. The experiment will run for a year. <06-04-2020: update: a little over one year from the publication date of this post, lockdown against COVID 19 was imposed in my province, and I was only slightly inconvenienced.>


My gut told me that there is more to be said about Christianity than what I wrote or implied in Post #50. My doubts about the completeness of my work began with this statement by Saint Paul:

“And if Christ be not risen, then is our preaching vain, and your faith is also vain.”

1 Corinthians 15:14, KJV

I was struck by the clarity and insistence of this impossible claim. What is going on here? We as theoreticians need to drill down here.

“Risen” means having come back from the dead, which is still an impossibility for modern medicine. However, Paul explains that what dies is a “natural body,” whereas what rises, or is “resurrected,” is a “spirit body,” which is “incorruptible.” The word “resurrection” does not appear in the Old Testament (Hebrew Bible), making its first appearance in Matthew, the first book of the New Testament. All things considered, the concept is obviously central to Christianity.

Postulate 1: Resurrection theology is an approximate theory, and as such, is allowed to contain an impossibility.

Postulate 2: Christianity is focused on taming a third stage of depopulation that follows the anger cycle and the sadness cycle if neither of these has returned population density to the reset value after a certain time (See Post #50 for explanations of these terms.). This is the total war stage, and it takes place on an international scale. Examples are WWI and WWII, which would be the international phases of national conflicts between a central-European majority and Serbs and Jews, respectively. Total war is arguably altruistic because each of two alliances or countries is helping the other with their population problem. The required signaling cycle seems to be that of the anger cycle but with the exchanged signals doing double duty as liquidation tactics. This is not just a fight, where the only consideration is what would be the shrewdest blow; there is a strong tendency to ape the opponent’s latest gambit, as expected in an exchange of signals "designed" to lock non-altruists out of the process. This psychology is called “sending back the bullet” in battlefield situations and “poetic justice” in everyday life. It is satisfying and it is a signal and it is illegal in peacetime, no matter that the other guy started it. In peacetime, you have to search elsewhere for your solutions than in mimicry and cooperation with a dangerous emotional program.

Furthermore, if you allow yourself to be drawn into a vendetta, you just wrote an “ = “ between yourself and the person you take exception to.

05-06-2022: The old, skeptical explanation of the resurrection, namely that the crucifixion was a fraud, deserves mention here. The New Testament mentions particular Romans and Pharisees sympathetic to Jesus. Extrapolating, I posit a pro-Jesus faction spanning all segments of that society and including many influential Romans and Pharisees, who would have had the resources necessary to pull off such a deception, but who could not openly interdict the crucifixion for lack of the necessary influence. Thus, the seeming miraculousness of the resurrection would in reality be a measure of the power of the illusion that groups identified as “The Enemy” are implacable and unitary. 

The total war program is well known for its destructiveness to the infrastructures of civilization, which suggests that the program evolved recently and is still being refined by natural selection. It may not even be older than agriculture, the last quantum leap in our ability to increase our numbers. That new ability may have generated the selection forces that brought forth the total war program.

Christian theology works a rational override on the anger cycle (See Post #41) by reassuring believers that they will be resurrected and therefore need not fear death. Since anger is fear in disguise, this reassurance undercuts the anger-cycle-like dynamics of the total war program.

Postulate 3: the corresponding exact theory of Christianity is that depopulation events always leave survivors and Christianity enhances your probability of being one of them. When population density has declined to the reset value, this should trigger a dramatic turnaround in the Zeitgeist from death-producing attitudes to nurturing ones, to start the population-density curve on its next long, slow upward climb. The resurrection of “spirit bodies” may refer to the re-establishment of life-valuing attitudes in Society.

03-25-2019: It follows that the human race is being selected for a predisposition to Christianity, and probably other religions as well.

The book of Revelation, the last book in the New Testament, appears to describe the sudden depopulation event that ends the population-density cycle. This is wrongly identified as the end of time/history, but remember that we deal here with an approximate theory.

Christian worship activities revolve around the Eucharist, a communal sharing and consumption of bread and wine. Its purpose is to eradicate the deepest roots of the fear of death, a fear that leads to the hatreds of the total-war emotional program. How does it work?

The Eucharist pacifies people by exposing them to the halting signal of the total war program. So, it halts. How did the consumption of bread and wine come to be the halting signal? Because they are made by people “playing with their food,” for the sake of variety, one imagines. However, this comes at the cost of caloric content (not caloric density) because the yeast always takes its cut. This practice will only make sense under conditions of plenty, which return with sufficient depopulation. Thus, alcohol (which I assume to be the active signaling ingredient) and leavened bread now signal to the human limbic system the return of abundance. I conjecture that these signals have a subtle pacifying effect, making it easier to resist tit-for-tat total-war signalling.

03-02-2024: Alternatively, Jesus may have been medicating the disciples with food and alcohol to keep their arousal level out of the panic zone at a time of peak emotion so that they could continue to function adaptively.

Wednesday, February 27, 2019

#50. A Naturalistic Theory of Worship [Evolutionary Psychology, Population]

Anytown, Canada, Apr. 11.

EP     PO     
Red, theory; black, fact.

Preamble

As discussed in Post #48, religion has a theory part and an applied part. I have termed the latter the ‘pragma’ of religion, which is basically the modes of worship. Since our moral codes are held by at least the Abrahamic religions to be commands from God, it would follow that it’s pretty important to conform to them, and most of us have difficulty doing this all the time. To help us, religion has developed a behavior-modification role, the role of the pragma.

The behavior-mod role aims at mitigating the human form of the Calhoun Effect–a tendency to aggression linked to rising population density but not to actual want per se. (For an introduction to Calhoun's research, see paragraph 7, Post #37.) Population density would have been an issue even millennia in the past when the world population was a minuscule fraction of what it is today, when people began living continuously inside walled cities for protection from their enemies. Within the inflexible confines of such a city, you have the makings of a human Calhoun experiment. Not coincidentally, the city of Jerusalem, sacred to three world religions, was a walled city. Nowadays, at a world population of 7.5 billion, it can be said that the world is our walled city. What can religion now tell us about how to get along?

I focus here on the Abrahamic religions: Judaism, Christianity, and Islam, which developed in that order, all in the Middle East, each of the last two acknowledging its debt to the previous. I suggest that these three religions form a series of progressively increasing effectiveness in mitigating the Calhoun Effect, by an accumulation of folkloric knowledge. Thus, to see how pragma works, the purpose of this post, we need only examine Islam, likely to represent the most efficient solution. Form generally follows function most transparently at highest efficiency.

The Human Calhoun Effect

In Post #40 I surmise that the natural human population density plot over time has a saw-tooth form, with linear increases alternating with abrupt decreases that return population density to some repeatable reset value. In Post #2, I surmise that the linear segments are created by a negative-feedback controller in the limbic system that controls rate-of-change of population density to a constant positive value, not absolute density. At this writing, the world is probably coming to the crest of one of these linear segments, which began in 1950. The sudden population-density decrease that ends the cycle is conjectured to have two phases: a first phase that produces population-density decrease by emigration, and a second phase that produces population-density decrease by mass murder, if the first phase does not take the system all the way to the reset value. The first phase accomplishes the biological function of dispersal, which is generally important for long-term species survival. The second phase guarantees overall stability on a multi-cycle time scale and wards off Malthusian catastrophes.

Both phases demand formally altruistic acts from individuals, but not of the warm-and-fuzzy kind. The first phase uses an exchange of anger signals (The “anger cycle,” see Post #41) to lock non-altruists out of the process so that the behavior is stable over evolutionary time. The second phase locks out the non-altruists using an asymmetric exchange of signals: contempt signals going one way and sadness signals going the other way. (See “The Sadness Cycle,” Post #41). The second phase culminates in the mass murder of the sadness signalers by the contempt signalers and the appropriation of all the resources of the sadness signalers by the contempt signalers. The last step guarantees that the contempt signalers will appear atrociously entitled to those outside the cycle.

Islam

Islam is conveniently summarized for our purposes as The Five Pillars of Islam, which are explained in the Quran, namely:
1) The Creed. (“There is no God but Allah, and Muhammad is the messenger of Allah.”)
2) Prayer.
3) Charity. (Concealed almsgiving is preferred.)
4) Fasting.
5) Pilgrimage.

The Theory

The creed is “The Great Why in the Sky” that people need for the control of their most difficult emotions. Strong emotion can be overridden by reason if that is required by a learned worldview, the validity of which the person is willing to bet their life on. (Here, I attempt to supply a worldview based on evolutionary psychology.) The creed, or “theory part” of a religion, also gets the rational mind cooperating with the behavior-modification program, which acts on the emotional self. 

04-03-2019: Rational override based on some creed may begin the work of extirpating someone's anger or sadness cycle, but behavior modification by pragma may be necessary to finish it and produce a lasting improvement in the person's circumstances. These cycles may have deep roots inaccessible to consciousness and capable of perpetuating self-defeating behaviors if not treated appropriately.

Prayer superficially is a deliberate wasting of time, which is not free in metabolic terms because the worshipper has a basal metabolic rate that must be supplied whether he/she works or not. Regular inactivity is surely a luxury of only those enjoying abundance. This is implicitly saying to the anger and sadness/contempt programs: “Food is still plentiful, so it’s not time to get nasty.” These cycles may be triggered by signs of high population density, not actual want, but they should still be sensitive to metabolic signals that speak to whether actual scarcity exists. High population density acquired its potent psychological effects, after all, because it usually predicted scarcity in the environment of evolutionary adaptedness. <06-14-2021: Alternatively, prayer may work like meditation to turn off the internal voice and the unnecessary stress it causes (if unscripted).>

Charity, on the receiving end, that is, is for contempt signalers, who, as you will recall, are extremely entitled in the final stage of their emotional program. Accepting charity–goods that you did not work for–tells the contempt program that it has achieved its mission and can therefore halt. So, it does. In Islam, almsgiving is said to be best done in secret, an effect of which will be to spare the pride of the recipient. One tends to think that this will be an issue with contemptuous types. Clearly, we are dealing here with someone whose contempt-signaler role has caused them to become downwardly mobile.

Fasting–going without the necessities of life–is for sadness signalers and it tells their emotional program that they have given or lost all their resources to the contempt signalers, and therefore their program has achieved its mission and can halt. So, it does. <11-21-2020: On the other hand, based on my own experience with fasting, the practice may work by increasing the faster's energy level post-fast, and an increased energy level can solve a multitude of problems.>

Pilgrimage is where you tell the anger-cycle program (with your feet) that you have been driven out of your homeland forever and must resettle elsewhere. Therefore, the program has achieved its mission and can halt. So, it does. This idea was expressed as “giving something to the dispersal drive” in Post #35.

Thus, the task of much religious behavior-modification can be likened to persuading a devil to depart by showing him false evidence that he has accomplished his purpose in coming, knowing that he is myopic. However, prayer tells him that he doesn’t even have to come in the first place.


Thursday, January 31, 2019

#49. The Reentrant-pathway Theory of Mental Illness [Neuroscience]


Red, theory; black, fact.

This theory is a further development of post #45, “The Denervation supersensitivity Theory of Mental Illness.

The basic idea here is that if a region of cerebral cortex is overgrown relative to a major synaptic partner, not only will it be starved of synaptic input from the partner, but it will also produce excess axons going to that partner that will have difficulty finding enough dendritic territories on which to synapse. Both difficulties can be solved at one stroke, however, if the overgrown area synapses on itself. The logic is similar to the application of valence rules in chemistry.

This mode of repair will produce cyclic signaling pathways (called “reentrant” in Neurospeak) that could support endlessly circulating neural activity. This is therefore an alternative way of getting what I have called “autonomous activity” from disregulated cortical growth, with no need to invoke the phenomenon of denervation supersensitivity. The loop circumnavigation time would have to be long enough to allow for the recovery of any refractory periods that may follow nerve-impulse firing.

The autonomous activity will give rise to hallucinations (called psychotic symptoms) if the re entrant pathway is in sensory cortex, and to manic behavior if in cortex with decidedly motoric functions, which would include planning. Since I have conjectured in these pages that an emotion is a high-level motor command, a re entrant pathway in frontal limbic cortex would produce an apparent emotion disconnected from conscious experience and if in posterior limbic cortex, a hallucinated emotion trigger.

The situation is very similar if a cortical area is normal in size but one of its main synaptic partners is reduced in size by disease. In epileptogenesis, the post-damage remodelling of the local neural networks is known to be associated with new-synapse formation and the sprouting of axon collaterals. The hyperexcitable brain tissue responsible for triggering seizures is known to lie just outside the dead core zone of the damaged region, and can therefore be called “overgrown” relative to the dead zone, which has zero functioning neurons.

All this is compatible with the formation, during the epileptogenesis latent period, of a pair of counter circulating, polysynaptic “ring roads” around the perimeter of the damaged area. This process would be determined by simple rules of valency satisfaction. Both ring roads would be capable of carrying autonomous activity that progresses to a seizure. This might only happen if inhibitory tone is also compromised. Hallucinations and seizures seem to be different grades of the same phenomenon.  Indeed, auditory hallucinations commonly occur in association with temporal-lobe seizures. The temporal lobe is the location of the auditory cortex (Brodmann areas 41 and 42).

Neural net repair leading to seizures.


Monday, December 31, 2018

#48. Science and Proto-science [evolutionary psychology]



Red, theory; black, fact.

Why does religion continue to be so popular in today's supposedly enlightened age? In what category of things should we place religion for purposes of analysis? This is a very important question. The least bad answer that I have come up with is: "Religion is the last protoscience." (By this I mean "classical protoscience"; a contemporary field of study, string theory, has also been labelled "protoscience," a result I base on a DuckDuckGo search on "Is string theory a protoscience?" on 20 Feb, 2022.)

Protoscience is most easily defined by a few well-known examples: alchemy and astrology. These disciplines can be thought of as crude, primordial versions of chemistry and astronomy, respectively, and unable to quickly divest themselves of laughably bad theories, due to an over-reliance on aesthetics as a way to truth.

If religion is a protoscience, that then, is the corresponding science? Will religion someday transform into some kind of super-science, marvelous beyond all prior imagining, and capable of robustly duplicating all the miracles of Christ, just for starters?

08-03-2020: Formerly at this location, now deprecated: Religion is the protoscience of origins and Darwin's theory its successor via the clergyman Malthus. Malthus was one of Darwin's influences, as attested explicitly in the writings of the latter.

07-26-2020: The science that could replace the protoscience religion is likely to be the study of adaptive, distributed, and unconscious behavioral effects in human populations. <07-30-2020: This will be a division within sociobiology focused on human swarm intelligence acting on an historical time scale.> From my own examined experience, I have reason to believe that such things exist. I called them "macro-homeostatic effects" in the post "The Drill Sergeants of the Apocalypse."

Alchemy is thought to have become chemistry with the isolation of oxygen in pure form by Priestly, followed in short order by its recognition as an element by Lavoisier, who had met Priestly in Paris and learned of the new "air" direct from the discoverer. This clue led Lavoisier to a correct theory of the nature of combustion. Priestly published his discovery of oxygen (Lavoisier's term), which he called "dephlogisticated air" (an alchemical term), in letter form, in 1775.

06-28-2019: The corresponding intellectual hand-off from astrology to astronomy seems to have been from Tycho Brae (1546-1601), who seems to have been much involved with astrology, to his onetime assistant Johannes Kepler (1571-1630; "The Legislator of the Heavens"), who derived three famous mathematical laws of planetary motion from Brae's data.

While the former astrology continues to this day as basically a form of amusement and favorite whipping-boy of sophomores everywhere who are just discovering the use of their brains, and the former alchemy has utterly perished (as theory, not practice), religion continues to pay its way down the time stream as a purveyor of a useful approximate theory.

An approximate theory is useful to have if all you need is a quick and dirty answer. The theory that the Earth is flat is an approximate theory that we use every time we take a step. The corresponding exact theory, that the Earth is spherical and gravitating, is only needed for challenging projects such as travelling to the moon.

03-13-2020: Thus, the God hypothesis is the theory of natural selection seen "through a glass darkly." However, the experiences contributing to the formulation of the God hypothesis would have been due to any cause of seemingly miraculous events over the horizon or beyond the reach of individual memory. This would comprise a mixture of the fastest effects of evolution and the slowest effects of synaptic plasticity/learning (e.g., developmental sensitive periods). However, the capacity for learning is itself due to natural selection and learning is, like natural selection, a trial-and-error process. Thus, the two sources of biological order hinting at the existence of God should usually be pulling in the same direction but perhaps with different levels of detail. Modern skepticism about religion seems to be directed at the intellectual anchor point: the God hypothesis. Since I believe that they are best de-faithed who are least de-faithed, let us simply shift the anchor to natural selection and carry on.

I think it premature to abandon classical religion as a source of moral guidance before evolutionary psychology is better developed, and given the usefulness of approximate theories, complete abandonment may never be practical. However, in our day, humanity is beset with many pressing problems, and although atheism appears to be in the ascendent, it may be time to reconcile religion with science, so as not to throw out any babies with the bathwater.

The modes of worship in use in many modern religions may well confer psychological benefits on the pious not yet suspected or articulated by mainstream science. Scientific investigation of the modes of worship that many religions have in common seems in order, especially since they amount to folk wisdom, which is sometimes on the money. Examples of common practices that seem to have potential for inducing neurophysiological changes are prayer, fasting, pilgrimage, incense-burning, and even simple congregating.

Photo by JJ Jordan on Unsplash

Sunday, December 30, 2018

#47. Body-mod Bob's [evolution, evolutionary psychology]




EV     EP     
Red, theory; black, fact.

In the previous post, "Goddesses of the Glacier," evolution appears to be operating in cooperation with a general capacity for technology. Natural selection operates on the brain pathways underlying our aesthetic preferences concerning our own appearance and that of possible reproduction partners and then a technology is automatically developed to satisfy them.

As a first example, consider the oil and brush technology previously assumed for differentiating women from men by hair smoothness. A further step in this direction is to posit that hair color may have been used to code gender. The first step would have been selection for a blond(e) hair colour in both women and men. Since this is a very light colour, it will show the effect of dyeing maximally. Concurrently with this, the aesthetic preferences of men and women would have been differentiated by selection, resulting in blonde women who experience a mild euphoria from being blonde and blond men who experience a mild dysphoria from the same cause. The men would predictably get busy inventing hair-dyeing technologies to rectify this. The necessary dyes are readily obtained from plant sources such as woad and walnut shells. The result would be an effective blonde-female/nonblond-male gender code.

This style of evolution could be very fast if the brain pathways of aesthetic preferences require few mutations for their modification compared with the number required for the equivalent direct modification of the body. Let us assume this and see where it leads.

Faster evolution is generally favored if humans are typically in competition with other species to be the first to occupy a newly possible ecological niche. Such niches will be created in abundance with every dramatic change in the environment, such as a glaciation and the following deglaciation. Possibly, these specific events just slide the same suite of niches to higher or lower latitudes, but the amount of land area in each is likely to change, leading to under-capacity in some, and thus opportunity. These opportunities will vanish much faster than evolution can follow unless a diversity of phenotypes is already present in the prospective colonizing population, which might happen as a result of genetic drift in multiple, isolated sub-populations.

If technologically assisted evolution has general advantages, then we can expect its importance to grow with increases in the reach of technology. Today, we seem to be at a threshold, with male-to-female and female-to-male gender transitions becoming well known. Demand for this service is probably being driven by disordered neural development during fetal life due to contamination of the fetus by environmental pollutants that have estrogenic properties (e.g., bisphenol A, PCBs, phthalates, etc.). The result is the birth of individuals with disordered and mutually contradictory, gendered aesthetic preferences, which is tragic. However, it is an interesting natural experiment.

With further development of cell biology in the direction of supporting body-modification technology, who knows what bizarre hankerings will see the light of day on demand from some customer? Remember that in evolution, the mutation comes first, and the mutation is random. Predictably, and sadly, most such reckless acts of self-indulgence will be punished by reduced employability and reduced reproductive success, doubtless exacerbated by prejudice on the part of the normal, normative majority.

However, the very occasional success story is also to be expected, involving the creation of fortuitously hyperfunctional individuals, and thus the technologically assisted creation of a new pre-species of human.

If the engineering details learned by the body-modification trade during this process are then translated into germ-line genetic engineering, then a true artificial humanoid species will have been created.
After the Pleistocene, the Plasticine.

Photo by Дмитрий Хрусталев-Григорьев on Unsplash